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PATHOGENETIC ASSESSMENT OF CLINICAL AND INSTRUMENTAL PARAMETERS OF THE LUNGS IN PATIENTS WITH DIABETES MELLITUS

Authors

DOI:

https://doi.org/10.34689/t0a38704

Keywords:

Type 1 and Type 2 Diabetes Mellitus, Abdominal Obesity, Bronchopulmonary Function, Pulmonary Ventilation, Spirometric Assessment, Metabolic Disturbances, Pulmonary Morphology

Abstract

Background: For the past two decades, many studies have investigated how diabetes mellitus (DM) affects the
bronchopulmonary system, but the results have been inconsistent. Diabetes mellitus leads to metabolic disorders and lack of
oxygen. And thus causes problems in the lungs and their vessels. One of the common diseases is increased ventilation of
the lungs.
Aim of the study is to identify the features and characteristics of the effect of diabetes mellitus and its concomitant
pathologies on the morphofunctional state of the respiratory system.
Materials and methods. The sample size was 395 people. A One Touch® glucose meter and a DCA-2000 MT analyzer
were used for laboratory and diagnostic assessment of the patients' condition. C-peptide, hormone levels, and insulin
resistance indices (Caro and HOMA-IR) were determined using standard laboratory techniques. Instrumental examinations
included chest X-rays, computer spirometry, and bronchoscopy.
Results. Lung function disorders were found in the study sample of patients: from bronchial obstruction in type 1
diabetes to restrictive and perfusion disorders in combination with type 2 diabetes with coronary heart disease and obesity.
Conclusion. As a result of the study, it was found that diabetes mellitus is associated with various disorders of
respiratory function, including restrictive and obstructive changes, as well as morphological changes in the lung tissue and
vascular system. Ultrasound revealed a complex of destructive and inflammatory changes in the lungs.
Keywords: Type 1 and Type 2 Diabetes Mellitus, Abdominal Obesity, Bronchopulmonary F

Author Biographies

  • Saule Zhautikova

    Professor of the Department of Physiology of NJSC «Karaganda Medical University», Gogol str. 40, Karaganda 100000, Kazakhstan. https://orcid.org/0009-0000-5712-7369; е-mail: zhautikova@qmu.kz; Cell phone +7 701 299 34 07

  • Nailya Urazalina

    Candidate of Medical Sciences, Associate Professor of the Department of physiological disciplines named after honored scientist of the republic of Kazakhstan, professor T.A. Nazarova, NJSC "Semey Medical University", Semey, Kazakhstan; phone: 8 777 907 55 89, е-mail: hakim_15@mail.ru, https://orcid.org/0000-0003-0200-1763

  • Gulnur Bakaramova

    Assistant Professor of the Department of Physiology of NJSC «Karaganda Medical University»,
    Gogol str. 40, Karaganda 100000, Kazakhstan. https://orcid.org/0009-0001-1169-9596; е-mail: Bakaramova@qmu.kz; Cell
    phone +7 778 675 33 64 

  • Diana Tolubayeva

    Doctor PhD “Medical Center Hospital of the President affairs Administration of the Republic of Kazakhstan” Astana, https://orcid.org/0000-0003-3119-7814; е-mail: dianajianna@gmail.com; Cell phone +7 701 299 34 06.

  • Gulyash Tanysheva

    Candidate of Medical Sciences, Head of the Department of Obstetrics and Gynecology, NCJSC «Semey Medical University», phone 8(777)153-53-57, email gulyash1965@mail.ru, https://orcid.org/0000-0001-9531-5950, Semey, Kazakhstan

  • Ainash Orazalina

    Candidate of Biological Sciences, Associate Professor, Head of the Department of Molecular Biology and Medical Genetics named after Academician of the National Academy of Sciences of the Republic of Kazakhstan T.K. Raisov, NJSC «Semey Medical University», phone; +7-777-235-47-72; e-mail: ainash.orazalina@smu.edu.kz; https://orcid.org/0000- 0003-4594-0138; Semey, Kazakhstan.

References

For citation: Zhautikova S.B., Urazalina N.M., Bakaramova G.A., Tolubayeva D.B., Tanysheva G.А., Orazalina A.S. Pathogenetic assessment of clinical and instrumental parameters of the lungs in patients with diabetes mellitus // Nauka i Zdravookhranenie [Science & Healthcare]. 2025. Vol.27 (2), pp. 31-38. doi 10.34689/SH.2025.27.2.004

Жаутикова С.Б., Уразалина Н.М., Бакарамова Г.А., Толубаева Д.Б., Танышева Г.А., Оразалина А.С. Патогенетическая оценка клинико-инструментальных показателей легких у больных сахарным диабетом // Наука и Здравоохранение. 2025. Т.27 (2), С. 31-38. doi: 10.34689/SH.2025.27.2.004

Жаутикова С.Б., Уразалина Н.М., Бакарамова Г.А., Толубаева Д.Б., Танышева Г.А., Оразалина А.С. Қант диабетімен ауыратын науқастарда өкпенің клиникалық-аспаптық көрсеткіштерін патогенетикалық бағалау // Ғылым және Денсаулық. 2025. Т.27 (2), Б. 31-38. doi: 10.34689/SH.2025.27.2.004

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2025-11-04

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How to Cite

PATHOGENETIC ASSESSMENT OF CLINICAL AND INSTRUMENTAL PARAMETERS OF THE LUNGS IN PATIENTS WITH DIABETES MELLITUS. (2025). Рецензируемый медицинский научно-практический журнал «Наука и здравоохранение», 27(2), 39-45. https://doi.org/10.34689/t0a38704

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